GeroScience Interest Group Winter Seminar Human T Cell Aging: Telomere Loss, Inflammation and Links to Disease

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The Trans-NIH GeroScience Interest Group (GSIG) is hosting a winter seminar featuring Dr. Rita Effros, Professor of Pathology and Laboratory Medicine in the David Geffen School of Medicine at the University of California Los Angeles. She directs research programs in the areas of aging and HIV disease, with emphasis on immunity to infection. Dr. Effros and colleagues have been at the forefront of studies on replicative senescence, telomeres and telomerase underlying this dysfunction. They have documented the existence of populations of T cells that increase with age and with HIV disease progression and which have overlapping molecular characteristics. They also examine the functional aspects of senescent T cells that may contribute to multiple pathologies of aging and AIDS, and are attempting to reverse or retard the process of replicative senescence in human T cells through manipulation of telomerase activity.

This event will be in Lipsett Amphitheater, Building 10, NIH. The seminar will also be videocast and archived in the GSIG web site.


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Human T Cell Aging: Telomere Loss, Inflammation and Links to Disease

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